Yeah, AD that's a tough one.
I heard about this study a while back related to a local case I have some indirect ties to. Anyway... the two things I think about related to the study are this:
1) No matter what surgery can do, one will always know what used to be, will still carry the psychological ramifications of a previous lifetime "lost."
2) Socially, people who have been gender-reassigned face persecution to the extreme. While things might be improving, the final truth is that a trans person likely faces a lifetime as a marginalized member of the larger community.
While I can see the social ramifications of gender reassignment improving over time as understanding among the general populous increases, I don't see the internal termoil as all the "fixable." We probably all have one or more trauma's form our past that we can't escape, and while we can cope, we know some scars never heal. When you're hard wired from as far back as memory goes back to believe you are a deeply, deeply flawed individual and meet with violent verification of this constantly through out your life, I don't see that being something that you can truly removed from your identity. Gender reassignment is ethically very tricky. I find it fascinating. Probably one far off day medicine will find a way to recognize and deal with it earlier on, which I think will make the prognosis a lot better for those who face it.