Great is subjective.
I think that apart from reader opinion Molly is clearly positioned as the "good female" in the strip, and contrasted sharply with Tina, as Bueller's chill, sexy girlfriend is contrasted with Bueller's uptight aggro sister. In the same wise, Tina is depicted as an aggressive, uncontrollably farting prostitute who is so debauched that she knows sex acts that aren't even on wikipedia, whereas Molly is cheery and positive, backing Beef up when he needs it, and game to satisfy him in bed but still very sensitive, such that she cries when Beef is weirded out by the human ears.
Now that I think about it more, perhaps Beef's winning of Molly is not so much a break from the Bueller film as a consummation of its promise. It was not so subtly hinted near the end of the film that the girlfriend and the depressed guy, Cameron I think his name was, sort of had a thing for one another. It's not unlikely that she found Cameron more interesting than the amusing but depthless blowhard that Bueller was, and that they hooked up after high school. Beef and Molly is in a sense this hookup, and their marriage thus marks a step in the great redressing of the power imbalance in the American high school - nerd finally wins, jock/popular guy suffers.