Flo's weird lack of a chin kills it for me.
I don't know why. When you're missing your chin... not like you lost it in an injury, not like you had a series of sad birth defects and missing a chin is just part of it, when you're a normal modestly-attractive person who happens to have no chin... that kills it for me. Especially with the clownish make-up she wears to draw the eye away from her total lack of anything a human being could call a chin.
I've just always assumed that she is someone's daughter or wife or lover or something, with how hard she gets pushed as being attractive in those ads despite looking like some kind of weird chinless hipster-Tammy-Faye-Bakker ersatz pastiche of a woman.
It is difficult to imagine someone looking at her casting photo off the street and thinking "yeah, that's our spokeswoman!"
Some kind of weapons-grade nepotism seems almost necessary for this to occur in a universe that still has laws underpinning it and stuff.